The Powerpuff Girls (1998)

S1E5 Octi Evil

The wicked Him plays with Bubbles' emotions by using Octi, her beloved stuffed toy, as his voice. Under Octi/Him's manipulative guidance, Bubbles stirs up trouble between her sisters, leading the Professor to put them on time-out until they can reconcile. Meanwhile, they plot to turn the enormous, Him-possessed Octi into squid meat.