Panty & Stocking with Garterbelt (2010)

S1E1 Excretion Without Honor or Humanity

Panty and Stocking must venture deep into the grimy sewers of Daten City to track down a ghost that's been preying on unsuspecting victims in public restrooms. As they navigate the foul-smelling tunnels, they face various bizarre challenges and encounters that test their resolve. With time running out, the sisters must confront the ghost before it can claim more victims and escape back into the shadows of the city.